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» Products   » Human Drugs (API's)   » Ciprofloxacin
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Ciprofloxacin
C.A.S No. 85721-33-1
Molecular Formula C17H18FN303
Chemical Name 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-quinoline-3-carboxylic acid
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  Test

 

Specification
  Description : Faintly yellowish to light Yellowish Crystalline Powder
  Solubilit : Soluble in Water, slightly soluble in Acetic Acid & in Methanol, very Slightly
Soluble in Ethanol, Practically insoluble in Acetone, Acetonitrile,Ethyl
Acetate, Hexana and in methylene chlorideldentification
  1) By infrared Spectrophotometer : 1) The Infrared absorption spectrum of sample should be concordant with the working standard.
  2) TLC   2) Compare with reference standard.
  pH of 2.5% w/v solution in Water : Between 3.00-4.50
  Water (by KF) : Between 4.70 % and 6.70% w/w
  Sulphated Ash : Not more than 0.10% w/w
  Sulphates : Not more than 0.04% w/w
  Heavy Metals : Not more than 0.002% w/w
  Fluoroquinolonic Acid   Not more than 0.20% w/w
  Relative Substances by HPLC    
 
» HPLC Puroty
» Ethylene Diamine Analog
» Individual Impurity
» Sum of impurities
 
» Not Less Than 99.50%
» Not Less Than 0.50% w/w
» Not Less Than 1.00% w/w
» Not Less Than 0.50% w/w
  Assay ( on dry basis)   Between 98.00% to 102.00%
  IN HOUSE TEST    
  UV of 2.5% W/V solution   NMT 0.05Abs
  In water at 450ml    
  Bulk density (Tapped)
  0.30 to 0.50gr/ml
 
USES
Ciprofloxacin is used to treat infections of the skin, lungs, airways, bones, and joints caused by susceptible bacteria. Ciprofloxacin is also frequently used to treat urinary infections caused by bacteria such as E. coli. Ciprofloxacin is effective in treating infectious diarrheas caused by E. coli, Campylobacter jejuni, and Shigella bacteria.
 
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