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» Products   » Human Drugs   » Tramadol Hydrochloride
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TRAMADOL HCL
C.A.S No. 22204-88-2
Molecular Formula C16H25NO2.HCl;C16H26ClNO2
Chemical Name (+/-)cis-2-((Dimethylamino)methyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride
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  Test   Specification
  Appearance : White crystalline powder
  Solubility : Freely soluble in water & in methanol, very slightly soluble in acetone.
  Identification    
  » Melting Point : 180 0 C to 184 0
  » Infrared Absorption Spectrum : To be concordant with standard Spectrum
  » TLC   To be corresponds with reference std. Chromatogram.
  » Chloride Test : It gives reaction of chlorides
  Appearance of Solution : Solution S is to be clear and colourless
 

Acidity

:

NMT 0.4 ml of 0.01M NaOH is required

  Optical Rotation :

0.1 ° to + 0.1 °

  Impurity E by TLC : NMT 0.2 %
  Related Substance by HPLC    
  » Impurity A : NMT 0.2%
  » Any other impurity : NMT 0.1%
  » Total impurities : NMT 0.4 %
  Heavy Metals : NMT 20 ppm
  Water : NMT 0.5 %
 
USES
Tramadol HCL is a popular pain reliever for many conditions that cause pain of all kinds. Whether you’ve got an abscessed tooth or post-operative pain, tramadol can be a great remedy for your pain. It works like an opiate, so that the pain relief offers maximum results, but it has the lower risk side effects associated with analgesics, making many people feel safer taking it than other medications. By taking the time to check out your options, you might realize that you’re better off taking tramadol than any other medication. However, only you and your doctor can make that decision, so you’ll need to discuss it with them.

DRUG CLASS AND MECHANISM:
Tramadol is a man-made (synthetic) analgesic (pain reliever). Its exact mechanism of action is unknown but similar morphine. Like morphine, tramadol binds to receptors in the brain (opioid receptors) that are important for transmitting the sensation of pain from throughout the body to. Tramadol, used for the treatment of pain,. Tramadol is not a nonsteroidal antiinflammatory drug (NSAID) and does not have the increased risk of stomach ulceration and internal bleeding that can occur with NSAIDs.
 
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